Important Pharmacology Topics for MBBS Students

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If you are an MBBS student, you must not skip studying about the drugs, that is, the subject of pharmacology. It is one of the core subjects of the MBBS, included in the para- clinical phases of the curriculum. During the course of MBBS, a student has to learn extensively about drug administration. The course curriculum and in-hand training in pharmacology enable the person to gain valuable knowledge about which drugs to prescribe, dosage of drugs, specific effects of their combinations, and modes of action of drugs on living beings, etc. Throughout the pharmacology course, an aspirant is expected to put forth consistent efforts. 


 A list of MBBS pharmacology important topics is given below. It must be noted that the topics mentioned below are covered over the entire duration of MBBS.

General Pharmacology

  • Route of Drug Administration
  • Bioavailability
  • Plasma Protein Binding
  • Pharmacovigilance
  • Microsomal enzyme and Enzyme Induction
  • First pass metabolism
  • Kinetics of Elimination
  • Loading dose and Maintenance dose
  • G protein coupled receptors
  • Therapeutic index
  • Factors modifying drug actions
  • Placebo, Rational prescribing
  • Tolerance
  • Teratogenicity

Autonomic Nervous System (ANS)

  • Myasthenia gravis
  • Atropine, Ipratropium bromide, Tiotropium, Dicyclomine
  • Drugs used in motion sickness
  • Treatment of Anticholinesterase
  • Cholinergic Drugs
  • Cholinesterase Reactivators
  • Glaucoma
  • OP Poisoning treatment
  • β-blockers (Complete)
  • Mydriatics
  • Pregalin, Phenylephrine, Epimedin

Autocoids

  • Second generation Antihistamines over the first generation- Advantages
  • Use of prostaglandin analogues
  • Migraine
  • Rheumatoid arthritis, Gout
  • Allopurinol, Aspirin, Sumatriptan, Probenecid
  • Classification of NSAIDs, Uses, Adverse effects

PNS

  • Local Anesthesia

GIT

  • Classification of treatment of peptic ulcer and drugs- mechanism of action and adverse effects
  • H2 Blockers- uses, adverse effects, mechanisms of actions
  • Proton pump inhibitors (PPI)
  • Antacids
  • Sucralfate
  • Prokinetic drugs (Metoclopramide, Domperidone)
  • 5-HT3 Receptor Antagonists

Endocrinology

  • Differences between Propylthiouracil and Carbimazole
  • Radioactive Iodine
  • Preparation of Insulin & Indications for Insulin
  • Diabetic Ketoacidosis
  • Biguanide (Metformin)
  • Corticosteroids
  • Anabolic steroid
  • Sildenafil & Tadalafil
  • Estrogen
  • Clomiphene Citrate
  • Selective Estrogen receptor modulators (SERMS)- Tamoxifen
  • Mifepristone
  • Oral contraceptives

Anti-microbial Agents (Very important section)

  • Drug Resistance
  • Prevention of Drug Resistance
  • Superinfections
  • Cotrimoxazole, Fluoroquinolones
  • Extended spectrum penicillin
  • β- lactamase inhibitors
  • Third generation cephalosporins
  • Aminoglycosides
  • First-line drugs for TB
  • Categories-wise treatment regimens for TB
  • Treatment of TB- Role of Corticosteroids
  • Amphotericin-B, Griseofulvin, Clotrimazole, Ketoconazole, fluconazole
  • Amantadine, Interferon
  • Nucleoside reverse transcriptase inhibitors
  • Classification of malarial drugs, chemoprophylaxis of metals
  • Treatment of uncomplicated malaria
  • Falciparum malaria – Treatment
  • Chloroquine, Quinine, Primaquine
  • Treatment of different forms of amoebic infection
  • Metronidazole, Mebendazole, Albendazole, DEC
  • Anti-retroviral drugs
  • Drugs used in Acne vulgaris

Anti-cancer drugs

  • Cyclophosphamide
  • Cisplatin
  • Methotrexate
  • Paclitaxel
  • Imatinib
  • Monoclonal Antibody

Cardiovascular System (CVS)

  • ACE Inhibitors
  • ARBs
  • Cardiacglycoside (Digoxin)
  • Calcium channels blockers (CCB)
  • Treatment of CHF
  • Treatment of Hypertension (Classification)
  • Treatment of Angina
  • Vasodilators
  • Hypertensive Emergency
  • Nicorandil, Nitrate, Lignocaine, Postmortem, Enalapril

Blood

  • Parenteral Iron preparation
  • Oral Anticoagulants
  • Anti-platelets
  • Low molecular weight
  • Warfarin
  • Deferiprone
  • Hypolipidemic Drugs

Kidney

  • Loop diuretics (Furosemide)
  • Mannitol
  • K Sparing diuretics (Spironolactone)

Chelating Agents

  • BAL (British anti-Lewiste)
  • Deferoxamine
  • Deferiprone

Central Nervous System (CNS)

  • Preanesthetic medication
  • Ketoamine
  • Antiepileptic drug
  • Status epilepticus
  • Anti-parkinsonian drugs and classification
  • Antipsychotic drug classification
  • Lithium carbonate, Diazepam
  • Antidepressants
  • Morphine, Acute morphine, Poisoning treatment, Buprenorphine
  • Opioid Antagonist

The above-mentioned list might seem too much or too difficult for a pharmacology aspirant, but it must be noted that there are some tips and tricks that make mastering the pharmacology concepts easy. The Gold Standard Faculty of Pharmacology advises aspirants to follow these tips to understand pharmacology better and become top doctors in due course of time.

  1. An aspirant should consult only the best pharmacology book for MBBS. A good book helps an aspirant have conceptual clarity. The distinctive and concise format of the content, eye-catching and detailed illustrations and photographs, tables and charts result in a better understanding of the nature of drugs.
  1. An aspirant should subscribe to a pharmacology course online, and rely on simplified ways of learning. In good-quality courses, pharmacology lectures are delivered in the form of videos. Interactive video lectures by renowned faculty help a student strengthen the basics of pharmacology and build a stronger foundation. The best pharmacology videos are highly illustrative and help the students ask questions in case they have a doubt and get explanations for the same. The good pharmacology courses also provides worthy notes and practice questions.

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